Targeted Therapy for Patients With Breast Cancer
Targeted therapy targets proteins on breast cancer cells that aid in them growing, spreading, and living longer, working to terminate cancer cells or diminish their growth. Their side effects differ from chemotherapy. Targeted therapy is administered intravenously or as a pill. Similar to chemotherapy, targeted drugs go into the bloodstream, reaching nearly all areas in the body, which is useful if the cancer has spread to other parts of the body. There are several different types of targeted therapy options for patients with breast cancer.
Targeted therapy for human epidermal growth factor receptor 2 breast cancer include:
- Monoclonal antibodies
- Antibody-drug conjugates
- Kinase inhibitors
Targeted therapy for hormone-receptor positive breast cancer include:
- CDK4/6 inhibitors
- mTor inhibitor
- PI3K inhibitor
Targeted therapy for those with BRCA gene mutations include:
- PARP inhibitors
Targeted therapy for triple-negative breast cancer include:
- Antibody-drug conjugate
Reference:
Targeted Drug Therapy for Breast Cancer. American Cancer Society. Updated August 25, 2022. Accessed September 20, 2022. https://www.cancer.org/cancer/breast-cancer/treatment/targeted-therapy-for-breast-cancer.html
